L-Glutathione (Reduced)
Glutathione
Glutathione (GSH) is the most abundant intracellular antioxidant, a tripeptide (γ-Glu-Cys-Gly) central to cellular redox homeostasis. Research has extensively studied its roles in neutralizing reactive oxygen species, supporting phase II detoxification via glutathione S-transferases, regenerating vitamins C and E, and modulating immune cell function. GSH depletion is associated with aging, oxidative disease, and neurodegenerative conditions, making it a key research tool.
Research Benefits
Key Research Applications
Documented areas of investigation based on peer-reviewed preclinical and clinical literature. For research reference only.
Oxidative Defense
Primary cellular antioxidant neutralizing reactive oxygen species across all cell types.
Detoxification
Supports phase II detoxification via glutathione S-transferase enzyme systems.
Immune Modulation
Studied for effects on T-cell proliferation and natural killer cell activity.
Redox Homeostasis
Regenerates vitamins C and E and maintains cellular redox balance.
Literature
Research Highlights
Primary cellular antioxidant defense against reactive oxygen species in all mammalian cells
GSH depletion linked to accelerated aging and neurodegeneration in preclinical models
Immune modulation via T-cell proliferation and NK cell activity enhancement
Hepatoprotective effects against acetaminophen-induced oxidative injury in rodent models
Specifications
Technical Data
Molecular Weight
307.32 g/mol
Sequence / Structure
γ-Glu-Cys-Gly
Storage Conditions
Lyophilized: −20°C, stable 24 months. Protect from light and oxygen. Reconstituted: 4°C, use within 7 days.
Solubility
Soluble in water at ≥10 mg/mL; prepare fresh to prevent oxidation
HPLC Purity
Verified — Batch VRC-GSH-2406
Testing Lab
Eurofins Scientific · Jun 2026
Research Areas
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For Research Purposes Only. Glutathione is sold exclusively for in vitro laboratory research. Not for human consumption, diagnostic, therapeutic, or veterinary use. Research highlights are summaries of published preclinical and clinical studies and do not constitute medical advice or claims of efficacy. See our Research Use Disclaimer.