Cibinetide / Non-Hematopoietic EPO Analog
ARA-290
Non-hematopoietic erythropoietin analog studied for neuroprotection, anti-inflammatory signaling, and tissue repair via innate repair receptor activation.
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Tested by: Eurofins Scientific · Batch: VRC-ARA-2407 · Jul 2026
About ARA-290
ARA-290 (cibinetide) is a synthetic 11-amino acid peptide derived from the helix B surface of erythropoietin (EPO), engineered to activate the innate repair receptor (IRR) — a heterodimer of the EPO receptor and the common beta chain — without triggering erythropoiesis. Preclinical research has studied its neuroprotective, anti-inflammatory, and tissue repair properties in models of neuropathic pain, diabetic neuropathy, sarcoidosis, and ischemic injury. It is a valuable research tool for dissecting EPO's cytoprotective functions from its hematopoietic effects.
Research Areas
Technical Specifications
Molecular Weight
1338.5 g/mol
Amino Acid Sequence
Gln-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser
Storage
Lyophilized: −20°C, stable 24 months. Reconstituted: 4°C, use within 28 days.
Solubility
Soluble in water at ≥1 mg/mL
For Research Purposes Only. ARA-290 is sold exclusively for in vitro laboratory research. Not for human consumption, diagnostic, therapeutic, or veterinary use. See our Research Use Disclaimer.