Growth Hormone Releasing Hormone Analog
CJC-1295
CJC-1295 is a synthetic analog of growth hormone-releasing hormone (GHRH) with a drug affinity complex (DAC) modification that enables covalent binding to serum albumin, dramatically extending its half-life compared to native GHRH. Preclinical and early clinical research has studied its ability to produce sustained, pulsatile GH release and elevate IGF-1 levels over extended periods. It is commonly used as a research tool in GH axis studies.
Research Benefits
Key Research Applications
Documented areas of investigation based on peer-reviewed preclinical and clinical literature. For research reference only.
GH Axis Stimulation
Promotes natural, pulsatile growth hormone release from the anterior pituitary.
IGF-1 Elevation
Supports insulin-like growth factor-1 production for downstream anabolic signaling.
Body Composition
Studied for effects on lean mass, adipose tissue, and metabolic rate in research models.
Bone Density
Investigated for bone mineral density support in GH-deficient preclinical models.
Literature
Research Highlights
Sustained GH elevation for 6–8 days post-administration in human subjects (Teichman et al., 2006)
Dose-dependent IGF-1 elevation in Phase I/II clinical studies
Preserved pulsatile GH secretion pattern unlike continuous infusion models
Synergistic GH release when combined with ipamorelin in preclinical models
Specifications
Technical Data
Molecular Weight
3647.28 g/mol
Sequence / Structure
Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH₂ (DAC)
Storage Conditions
Lyophilized: −20°C, stable 24 months. Reconstituted: 4°C, use within 28 days.
Solubility
Soluble in water at ≥1 mg/mL
HPLC Purity
Verified — Batch VRC-CJC-2405
Testing Lab
Eurofins Scientific · May 2026
Research Areas
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For Research Purposes Only. CJC-1295 is sold exclusively for in vitro laboratory research. Not for human consumption, diagnostic, therapeutic, or veterinary use. Research highlights are summaries of published preclinical and clinical studies and do not constitute medical advice or claims of efficacy. See our Research Use Disclaimer.