Afamelanotide / MT-1
Melanotan I
Synthetic melanocortin analog studied for melanogenesis, photoprotection, and MC1R pathway research in preclinical models.
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Tested by: Intertek Pharmaceutical Services · Batch: VRC-MT1-2406 · Jun 2026
About Melanotan I
Melanotan I (afamelanotide) is a synthetic analog of α-melanocyte-stimulating hormone (α-MSH) with enhanced metabolic stability. It acts as a non-selective melanocortin receptor agonist with preference for MC1R, stimulating melanogenesis and eumelanin production. Preclinical and clinical research has studied its role in photoprotection, erythropoietic protoporphyria, and melanocortin pathway biology. An FDA-approved form (Scenesse) exists for erythropoietic protoporphyria.
Research Areas
Technical Specifications
Molecular Weight
1646.87 g/mol
Amino Acid Sequence
Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH₂
Storage
Lyophilized: −20°C, stable 24 months. Reconstituted: 4°C, use within 28 days.
Solubility
Soluble in water at ≥1 mg/mL
For Research Purposes Only. Melanotan I is sold exclusively for in vitro laboratory research. Not for human consumption, diagnostic, therapeutic, or veterinary use. See our Research Use Disclaimer.