KiSS-1 Derived Peptide / GPR54 Agonist
Kisspeptin
Endogenous GPR54 agonist studied for GnRH pulse regulation, LH/FSH secretion, reproductive axis activation, and hypothalamic-pituitary-gonadal axis research.
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Tested by: Intertek Pharmaceutical Services · Batch: VRC-KSP-2407 · Jul 2026
About Kisspeptin
Kisspeptin (KiSS-1 derived peptide) is an endogenous neuropeptide encoded by the KISS1 gene that acts as the primary activator of the hypothalamic-pituitary-gonadal (HPG) axis. It binds GPR54 (KISS1R) receptors on GnRH neurons, triggering pulsatile GnRH release and downstream LH and FSH secretion. Preclinical and clinical research has studied its role in puberty onset, reproductive cyclicity, fertility regulation, and hypogonadism. It is a key research tool in reproductive endocrinology, HPG axis biology, and neuroendocrine research. Multiple isoforms (Kisspeptin-10, -13, -14, -54) have been characterized.
Research Areas
Technical Specifications
Molecular Weight
1302.5 g/mol (Kisspeptin-10)
Amino Acid Sequence
Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂ (Kisspeptin-10)
Storage
Lyophilized: −20°C, stable 24 months. Reconstituted: 4°C, use within 28 days.
Solubility
Soluble in water at ≥1 mg/mL
Related Compounds
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For Research Purposes Only. Kisspeptin is sold exclusively for in vitro laboratory research. Not for human consumption, diagnostic, therapeutic, or veterinary use. See our Research Use Disclaimer.