Bremelanotide
Melanocortin receptor agonist studied for its role in sexual arousal and CNS-mediated pathways in preclinical research.
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Tested by: SGS Life Sciences · Batch: VRC-PT1-2406 · Jun 2026
PT-141 (Bremelanotide) is a cyclic heptapeptide melanocortin receptor agonist derived from the tanning peptide Melanotan II. It acts centrally via MC3R and MC4R receptors in the hypothalamus, distinguishing it from PDE5 inhibitors that act peripherally. Preclinical and clinical research has studied its role in sexual arousal pathways, CNS-mediated desire signaling, and its potential in hypoactive sexual desire disorder (HSDD) models.
Research Areas
Technical Specifications
Molecular Weight
1025.18 g/mol
Amino Acid Sequence
Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
Storage
Lyophilized: −20°C, stable 24 months. Reconstituted: 4°C, use within 28 days.
Solubility
Soluble in water at ≥1 mg/mL
For Research Purposes Only. PT-141 is sold exclusively for in vitro laboratory research. Not for human consumption, diagnostic, therapeutic, or veterinary use. See our Research Use Disclaimer.