Mitochondrial Open Reading Frame Peptide
MOTS-c
Mitochondria-derived peptide studied for metabolic regulation, insulin sensitivity, and exercise mimetic effects in preclinical models.
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Tested by: SGS Life Sciences · Batch: VRC-MOT-2406 · Jun 2026
About MOTS-c
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA type-c) is a mitochondria-derived peptide encoded within the mitochondrial genome. Preclinical research has investigated its role as a metabolic regulator, with studies showing effects on insulin sensitivity, glucose uptake, AMPK activation, and exercise-like metabolic responses. It is studied as a potential tool compound in metabolic disease, aging, and exercise physiology research.
Research Areas
Technical Specifications
Molecular Weight
2174.5 g/mol
Amino Acid Sequence
Tyr-Trp-Leu-Thr-Lys-Leu-Ile-Thr-Tyr-Leu-Lys-Lys-Gly-Glu-Ile-Lys-Glu-Leu-Leu-Glu-Lys-Leu-Glu-Glu-Leu-Lys-Lys-Leu-Lys-Glu-Glu-Leu-Glu-Lys
Storage
Lyophilized: −20°C, stable 24 months. Reconstituted: 4°C, use within 28 days.
Solubility
Soluble in water at ≥1 mg/mL
For Research Purposes Only. MOTS-c is sold exclusively for in vitro laboratory research. Not for human consumption, diagnostic, therapeutic, or veterinary use. See our Research Use Disclaimer.