GLP-1 Receptor Agonist
GLP-1 receptor agonist studied in metabolic regulation, appetite signaling, and glucose homeostasis research.
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Tested by: SGS Life Sciences · Batch: VRC-SEM-2406 · Jun 2026
Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist with 94% sequence homology to human GLP-1. It features a C18 fatty diacid chain enabling albumin binding and extended half-life. Preclinical and clinical research has extensively studied its role in glucose-dependent insulin secretion, appetite suppression via hypothalamic pathways, gastric emptying delay, and body weight regulation. It is widely used as a research tool in metabolic disease models.
Research Areas
Technical Specifications
Molecular Weight
4113.58 g/mol
Amino Acid Sequence
His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(C18 diacid)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg
Storage
Lyophilized: −20°C, stable 24 months. Reconstituted: 4°C, use within 28 days.
Solubility
Soluble in 10mM PBS pH 7.4 at ≥1 mg/mL
For Research Purposes Only. Semaglutide is sold exclusively for in vitro laboratory research. Not for human consumption, diagnostic, therapeutic, or veterinary use. See our Research Use Disclaimer.