Elamipretide / Szeto-Schiller Peptide
SS-31
Mitochondria-targeted tetrapeptide studied for cardiolipin binding, mitochondrial membrane protection, and oxidative stress reduction in preclinical models.
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Tested by: SGS Life Sciences · Batch: VRC-SS3-2407 · Jul 2026
About SS-31
SS-31 (elamipretide, D-Arg-2′6′-Dmt-Lys-Phe-NH₂) is a cell-permeable, mitochondria-targeted tetrapeptide from the Szeto-Schiller peptide family. It selectively concentrates in the inner mitochondrial membrane where it binds cardiolipin, stabilizing cristae architecture and protecting electron transport chain complexes. Preclinical research has studied its role in reducing mitochondrial ROS, improving ATP production, and protecting against ischemia-reperfusion injury. It is a key research tool in mitochondrial biology, aging, and cardiac research.
Research Areas
Technical Specifications
Molecular Weight
639.80 g/mol
Amino Acid Sequence
D-Arg-2′6′-Dmt-Lys-Phe-NH₂
Storage
Lyophilized: −20°C, stable 24 months. Protect from light. Reconstituted: 4°C, use within 14 days.
Solubility
Soluble in water at ≥5 mg/mL
For Research Purposes Only. SS-31 is sold exclusively for in vitro laboratory research. Not for human consumption, diagnostic, therapeutic, or veterinary use. See our Research Use Disclaimer.